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Sjogren syndrome is an autoimmune disorder in which the glands that produce tears and saliva are destroyed. The condition may affect many different parts of the body, including the kidneys and lungs.
Alternative NamesXerostomia-Sjogren syndrome; Keratoconjunctivitis sicca-Sjogren's
Causes, incidence, and risk factorsThe cause of Sjogren syndrome is unknown. The syndrome occurs most often in women ages 40 - 50. It is rare in children. Young patients usually have signs of another autoimmune disorderfirst.
The syndrome may be associated with:
Sjogren syndrome affects about 1 - 4 million people in the United States.
SymptomsDryness of the mouth and eyes are the most common symptoms of this syndrome.
Eye symptoms:
- Itching eyes
- Feeling that something is in the eye
Mouth and throat symptoms:
- Difficulty swallowing or eating
- Loss of sense of taste
- Difficulty speaking
- Thick or stringy saliva
- Mouth sores or pain
- Hoarseness
Other symptoms may include:
- Fatigue
- Fever
- Change in the color of hands or feet
- Joint pain or joint swelling
- Swollen glands
A physical examination reveals dry eyes and mouth. There may be mouth sores because of the mouth dryness.
Tests:
- Schirmer's test
- Antinuclear antibodies (ANA) test
- Salivary gland biopsy
- Rheumatoid factor (possible)
- Tear test
- Slit lamp examination with rose bengal dye
The goal is to relieve symptoms. Dry eyes may be treated with artificial tears, eye-lubricating ointments, or cyclosoporine liquid. Tiny plugs can be placed in the tear drainage ducts to help the tears stay on the surface of the eye.
Disease modifying drugs (DMARDs) similar to those used for rheumatoid Arthritis may improve the symptoms of Sjogren syndrome. These include tumor necrosis factor (TNF) inhibiting drugs.
Sipping water throughout the day and chewing sugarless gum may help relieve mouth dryness. Avoid medicines that can cause mouth dryness such as antihistamines and decongestants. Avoid alcohol.
Talk with your dentist about:
- Solutions to replace minerals in your teeth
- Saliva substitutes
- Drugs that help your salivary glands make more saliva
Frequent brushing and flossing of the teeth, and regular dental visits may prevent severe dental cavities caused by dry mouth.
Arthritissymptoms are commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy.
Expectations (prognosis)The disease is usually not life-threatening. The outcome depends on what other diseases you have.
There is an increased risk of lymphoma.
Complications- Kidney failure(rare)
- Lymphoma
- Pulmonary infection
- Vasculitis (rare)
Call for an appointment with your health care provider if you develop symptoms of Sjogren syndrome.
ReferencesKruszka P, O'Brian RJ. Diagnosis and management of Sjogren syndrome. Am Fam Physician. 2009;79:465-470.
Taubert M, Davies MR, Black I. Dry Mouth. BMJ. 2007;334:534.
What else can I help you with?
Can yoube diagnosed with Sjogren Syndrome and not have Lupus or Rheumatoid arthritis?
Sjogren's syndrome where there is gland inflammation causing dry eyes and mouth, etc.) which is not associated with another connective tissue disease is called primary Sjogren's syndrome. When Sjogren's syndrome associated with a connective tissue diseases, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma, as well it is referred to as secondary Sjogren's syndrome.
Is sjogren's syndrome dangerous?
No
Can Sjogren's syndrome cause Vasculitic neuropathy?
Hello, I see you are asking "What are the causes for marinesco-sjogren syndrome-neuropathy?" Genetic Disease. Marinesco-Sjogren syndrome is a genetic disease, which means that it is caused by one or more genes not working correctly. For more information, you can visit this URL - mentalhealthhelpcenter. com/condition/marinesco-sjogren-syndrome-neuropathy/c/27844
What is Sjogren-Larsson syndrome?
Sjogren-Larsson syndrome is an inherited condition resulting in thickened, dry, rough skin (ichthyosis), mental retardation , and stiff, rigid muscles (spasticity ).
What is sjeogren syndrome?
Sjogren's syndrome is an autoimmune disease that causes chronic dry mouth and eyes.
What is the correct spelling of sjogren's syndrome?
The correct spelling of the autoimmune disease includes the capitalization of the proper name and the umlaut "ö", as Sjögren's syndrome. However, common English use has the normal letter "o", as Sjogren's syndrome.
Can Sjogren's syndrome cause Secondary vasculitis?
Yes, Sjogren's syndrome can lead to secondary vasculitis in some cases. Vasculitis is inflammation of blood vessels, and it can occur as a complication of autoimmune diseases like Sjogren's syndrome. The immune system attacks the body's own tissues, including blood vessels, leading to vasculitis. Treatment typically involves managing the underlying autoimmune condition and addressing the vasculitis symptoms with medications like corticosteroids or immunosuppressants.
What is the cause of Sjogren-Larsson syndrome?
Sjogren-Larsson syndrome is inherited in an autosomal recessive fashion, meaning that an affected child has received a faulty gene from both the mother and the father. The disorder has been traced to a variety of defects on chromosome 17.
What is the prognosis for Sjogren-Larsson syndrome?
Sjogren-Larsson syndrome is a rare autosomal recessive disorder characterized by a triad of symptoms: ichthyosis, intellectual disability, and spastic diplegia. The prognosis for individuals with Sjogren-Larsson syndrome varies depending on the severity of symptoms, but generally, it is a lifelong condition that requires multidisciplinary management to address the skin, neurological, and developmental aspects of the disorder. Early intervention and supportive care can help improve quality of life and functional outcomes for affected individuals.
What is showgrams disease?
Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms - dry eyes and a dry mouth. Sjogren's syndrome often accompanies other immune-system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first - resulting in decreased production of tears and saliva. Although you can develop Sjogren's syndrome at any age, most people are older than 40 at the time of diagnosis. The condition is much more common in women. Treatment focuses on relieving symptoms, which often subside with time.
Can Sjogren-Larsson syndrome be diagnosed before birth?
In families who have an increased risk of Sjogren-Larsson disease, prenatal diagnosis can be accomplished through amniocentesis, chorionic villi sampling, or fetal skin biopsy.
How is Sjogren-Larsson syndrome treated?
There are no treatments that can cure Sjogren-Larsson syndrome. A number of lotion or cream preparations (including mineral oil, urea, and vitamin D-3) may help improve itching and flaking, decrease the speed of skin turnover.
