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Glycogen is extracted from animal tissue. This tissue is actually pretty tough and to liberate the glycogen from it, the tissue has to be ruptured, broken down nicely, so that all the glycogen is available for extraction. This grinding (homgenizing) process is aided by the presence of sand and TCA (Tri-Chloro Acetic acid). TCA is a higly corrosive agent and helps in rupturing the tissue.

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Grinding of the sand and TCA is necessary in preparing glycogen to break down the tissue and release the glycogen molecules. The grinding and TCA treatment help disrupt the cell structure and denature any enzymes that may break down the glycogen. This process ensures efficient extraction and purification of glycogen from the tissue.


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