Approximately 220 miles.
146 miles
Sanibel Island is about 25 Km west opf South West Florida International at Ft. Myers.
67 miles
about 180 miles
23 miles
20 mins
The driving distance is 1,479 miles.
93 miles
54 miles
Fort Myers is approximately 20 miles from Sanibel Island, Florida. The drive typically takes around 30 to 40 minutes, depending on traffic and the route taken. You can reach Sanibel Island via the Sanibel Causeway, which offers scenic views along the way.
145 miles
It is 167.38 miles according to MapQuest.