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As of October 2023, several major airlines operate out of Detroit Metropolitan Wayne County Airport (DTW), including Delta Air Lines, Spirit Airlines, American Airlines, United Airlines, and Southwest Airlines, among others. In total, more than 15 airlines provide domestic and international flights from this hub. The airport is a key travel point in the Midwest, facilitating a wide range of destinations. For the most current information, it's best to check the airport's official website or resources.

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