The Spanishexplorers first brought gum to the Midwest.(I know this answer is wrong, so if you do know it, tell me)
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European explorers began to use gunpowder in order to take slaves captive. This was first done on the continent of Africa.
There were ancient horses native to the Americas, but they went extinct prior to human civilizations being founded. The current mustang population of the American West, the Chincoteague Ponies and other feral horse populations are all descendants of horses and ponies brought over by the European explorers, settlers and conquistadors.
The first major impact of the exploration of the New World was due to the early start Spain had in its exploration of the New World. Spanish conquistadors and explorers defeated Native American Tribes and with that came the shipping of gold back to Spain. This led to the submission of the Inca & Aztec Tribal empires.
European
King Charles II was the first spanish king to send African slaves to the Americas.