Eight presidents have died in office. Obama is our 44th president. 8/44 = 18 percent.
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As of 2014, there have been four US Presidents that have died in office of natural causes. The presidents include William Henry Harrison, Zachary Taylor, Warren G. Harding, and Franklin D. Roosevelt.
Reagan
A term
Office of Management and Budget
There were actually four presidents to die in office during the 20th Century, though only two died of natural causes. William McKinley starts us off on September 14, 1901- Assassinated Warren G. Harding- August 2, 1923- Either heart attack or stroke Franklin D. Roosevelt- April 12, 1945- Cerebral Hemorrhage John F. Kennedy- November 22, 1963- Assassinated