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The Spanish had a technological advantage, having steel weapons, guns, and horses. Many Native Americans had never seen these before, and were terrified of them. Also, the two empires were not completely unified, but made of dozens of different tribes and peoples conquered by the Aztecs and Incas. The Spaniards took advantage of this by making alliances with those vengeful tribes. But the most deadly weapon the Spanish had was disease. Most Europeans were immune to smallpox, but Native Americans were not. Smallpox wiped out thousands of people in the Americas, including the emperor of Inca himself, thus making them easy to conquer.

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