The Keskydees, or Kaskaskias, were a Native American tribe historically located in the Illinois region, primarily associated with the Mississippi River. They were part of the larger Algonquian-speaking group and played a significant role in early American history, particularly during European colonization. The tribe faced significant challenges due to disease, warfare, and displacement, leading to a decline in their population and influence. Today, their legacy is part of the broader narrative of Indigenous peoples in North America.