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Chemical factors, such as levels of carbon dioxide (CO2), oxygen (O2), and pH in the blood, significantly influence breathing patterns. Increased CO2 levels or decreased O2 levels stimulate chemoreceptors that signal the respiratory center in the brain to increase the rate and depth of breathing, enhancing gas exchange. Conversely, a rise in blood pH (alkalosis) may slow respiration, while a drop (acidosis) typically accelerates it. These adjustments help maintain homeostasis and ensure that the body's metabolic needs are met.

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