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Perhaps the most commonly known (and used) change in proteins after a living organism dies, is that they begin to switch chirality (or "handedness"). This means that they change from their normal L-form (or "left-handed") to D-form (or "right-handed") molecules. In fact, this chiral change is sometimes used in forensics to estimate a time of death for the organism.

Protein compounds are also degraded into ammonia containing compounds, which help give dead bodies their well known stench.

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