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Professor X of The X-Men - Head of the mutant school founder of the X-Men, Professor Xavier is paraplegic and in a wheelchair.

Joe Swanson of Family Guy - A wheelchair bound police officer, Joe Swanson was injured while stopping the Grinch from stealing Christmas.

Daredevil of Marvel Comics - Matt Murdoch was blinded as a child in the Hells Kitchen neighborhood. Despite his blindness, he went on to be an attorney. He use the information from his cases to carry out vigilante work as The Daredevil. The Daredevil helped to bust up the city's crime syndicates.

Alicia Masters of The Fantastic Four - Alicia was a blind sculptor in the series. She was the love interest of one of the heroes in The Four, Thing.

Nemo of Finding Nemo - Nemo had one fin that did not grow correctly. It caused him problems with his swimming and was often an obstacle for him. Some of Nemo's friends wanted to baby him because of it, but others pushed him to get out there and figure out how to push through situations.

Dory of Finding Nemo - Dory suffered from short term memory loss. However, she was very positive and tried to help where she could. Although she could be frustrating at times, her good hearted nature won her some good friends.

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