Hemolysis is the breakdown of red blood cells.
See also: Hemolytic anemia
InformationRed blood cells normally live for 110 - 120 days. After that, they naturally break down and are usually removed from the circulation by the spleen.
Some diseases and processes cause red blood cells to break down too soon. This requires the bone marrow to make more red blood cells than normal. The balance between red blood cell breakdown and production determines how low the red blood cell count becomes.
Conditions that can cause hemolysis include:
Scwartz RS. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 164.
Gregg XT, Prchal JT. Red blood cell enzymopathies. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 45.
Gallagher PG, Jarolim P. Red blood cell membrane disorders. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 46.
Powers A, Silberstein LE. Autoimmune hemolytic anemia. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 47.
Schrier Sl, Price EA. Extrinsic nonimmune hemolytic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 48.
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Haemolysis is when red blood cells are broken open so that the cytoplasm within them is released into the bloodstream. It can occur in humans as a result of several different medical problems.
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Haemolysis is the the rupture or destruction of red blood cells.
how erythroctes can show various forms of haemolysis in hypotonic solution
haemolysis
The disruption of red blood cell and release of their haemoglobin. There are several types of haemolytic reactions when bacteria such as streptococci or staphylococcus grow on blood agar.
Sabah A. A. Jassim has written: 'Aspects of staphylococcal growth, haemolysis and phagocytosis'
Excessive squeezing will cause haemolysis of the sample, i.e., the rupture of red blood cells, thus releasing their content (Hb and electrolytes) into the plasma. Haemolysis will alter potassium, ionised calcium (ICa), phosphate and enzymes. If gross haemolysis occurs, all results may be affected, due to a dilution of the sample by dissolved haemoglobin. Tissue fluid (resulting in increased potassium levels) may also contaminate the blood sample if you squeeze too hard.
Causes invasive infections; more severe and less common. Infects bloods and organs.
Glacial Acetic Acid
rbcs usually becomes swollen or haemolyse in hypotonic solution, this is due to osmosis. In this case, the concentration of solute is more inside the rbc, hence it exerts osmotic pressure which draws water from lower osmotic solution. The rbc swells to its limit because of its biconcave structure and burst after crossing its limit (haemolysis)
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