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Any insufficiency in the delivery of blood to the body is fatal. Chronic insufficiency interferes with oxygen exchange in the lung, the function of the kidneys and liver function. In order to keep the blood flow to the body constant the circulatory system (heart, lung, kidney and blood vessels) work together to maintain internal oxygen concentrations within a very narrow range. The heart, as the pump, works to keep the blood pressure constant, so if the heart begins blood pressure will drop too much.

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