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Rheumatoid arthritis is an autoimmune disease which cause the joints in the body to be constantly inflamed. This disease results when body tissues are?
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∙ 8y ago
the reason for RA is stil not understood.
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∙ 8y ago
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What is rheumatoid arthritis?
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. RA can be responsible for inflammation around the joints as well as in other organs and tissues of the body. An autoimmune disease is a condition where body's tissues are attacked by the body's own immune system. The immune system is designed to "seek and destroy" invaders or foreign materials of the body, especially infectious organisms. Persons with autoimmune diseases have antibodies in their blood that attack their own body the resulting inflammation then damages or destroys the tissue concerned. Because it can affect several organs of the body it is known as a systemic illness and is sometimes called rheumatoid disease. Rheumatoid arthritis is a chronic illness, meaning it can last for years, patients may experience long periods of time without symptoms. Rheumatoid arthritis is a progressive illness that has the potential to cause joint destruction, Deformity, pain and functional disability. Ra usually presents itself in several joints coinciding on on opposite sides of the body and is also described as a poliarthritis.Kids can get rheumatoid arthritis too. Most people think that it is only the elderly that can get it. The Arthritis Foundation, a nationwide support group, works to bring this message out to the world.Rheumatoid arthritis is an Autoimmune disease that leads to the destruction of connective tissue like cartilage in the joints and in other places.
What are the joint symptoms of arthritis?
The term that relates to arthritis in the case of juveniles is "Juvenile idiopathic arthritis" which is an autoimmune disease that usually first shows itself as several joints becoming inflamed and stiff at the same time. For more info on this condition go to the related link below (Juvenile idiopathic arthritis)
What is the basic pathology of rheumatoid arthritis?
What are causes and risk factors of rheumatoid arthritis?The cause of rheumatoid arthritis is unknown. Even though infectious agents such as viruses, bacteria, and fungi have long been suspected, none has been proven as the cause. The cause of rheumatoid arthritis is a very active area of worldwide research. It is believed that the tendency to develop rheumatoid arthritis may be genetically inherited (hereditary). Certain genes have been identified that increase the risk for rheumatoid arthritis. It is also suspected that certain infections or factors in the environment might trigger the activation of the immune system in susceptible individuals. This misdirected immune system then attacks the body's own tissues. This leads to inflammation in the joints and sometimes in various organs of the body, such as the lungs or eyes. It is not known what triggers the onset of rheumatoid arthritis. Regardless of the exact trigger, the result is an immune system that is geared up to promote inflammation in the joints and occasionally other tissues of the body. Immune cells, called lymphocytes, are activated and chemical messengers (cytokines, such astumor necrosis factor/TNF, interleukin-1/IL-1, and interleukin-6/IL-6) are expressed in the inflamed areas.Environmental factors also seem to play some role in causing rheumatoid arthritis. For example, scientists have reported thatsmoking tobacco, exposure to silica mineral, and chronic periodontal disease all increase the risk of developing rheumatoid arthritis.What are rheumatoid arthritis symptoms and signs?The symptoms of rheumatoid arthritis come and go, depending on the degree of tissue inflammation. When body tissues are inflamed, the disease is active. When tissue inflammation subsides, the disease is inactive (in remission). Remissions can occur spontaneously or with treatment and can last weeks, months, or years. During remissions, symptoms of the disease disappear, and people generally feel well. When the disease becomes active again (relapse), symptoms return. The return of disease activity and symptoms is called a flare. The course of rheumatoid arthritis varies among affected individuals, and periods of flares and remissions are typical. When the disease is active, symptoms can include fatigue, loss of energy,lack of appetite, low-grade fever, muscle and joint aches, and stiffness. Muscle and joint stiffness are usually most notable in the morning and after periods of inactivity. Arthritis is common during disease flares. Also during flares, joints frequently become red, swollen, painful, and tender. This occurs because the lining tissue of the joint (synovium) becomes inflamed, resulting in the production of excessive joint fluid (synovial fluid). The synovium also thickens with inflammation (synovitis).Rheumatoid arthritis usually inflames multiple joints in a symmetrical pattern (both sides of the body affected). Early symptoms may be subtle. The small joints of both the hands and wrists are often involved. Symptoms in the hands with rheumatoid arthritis include difficulty with simple tasks of daily living, such as turning door knobs and opening jars. The small joints of the feet are also commonly involved, which can lead to painful walking, especially in the morning after arising from bed. Occasionally, only one joint is inflamed. When only one joint is involved, the arthritis can mimic the joint inflammation caused by other forms of arthritis, such as gout or joint infection. Chronic inflammation can cause damage to body tissues, including cartilage and bone. This leads to a loss of cartilage and erosion and weakness of the bones as well as the muscles, resulting in joint deformity, destruction, and loss of function. Rarely, rheumatoid arthritis can even affect the joint that is responsible for the tightening of our vocal cords to change the tone of our voice, the cricoarytenoid joint. When this joint is inflamed, it can cause hoarseness of the voice. Symptoms in children with rheumatoid arthritis include limping, irritability, crying, and poor appetite.
Can a person get rheumatoid arthritis in jaws?
Temporomandibular joint (TMJ) and the muscles that control chewing. TMJ disorders fall into three main categories: myofascial pain, internal derangement of the joint, and degenerative joint disease, such as osteoarthritis or rheumatoid arthritis in the jaw joint.
What is rheumatoid arthrist?
Arthritis causes swelling, reduced mobility and pain generally of the joints. I hope you never get it. -- The word "arthritis" is taken from Greek words meaning "inflamed joints". It is associated with a group of well over 100 rheumatic diseases and conditions, which may affect not only the joints but also the muscles, bones, tendons, and ligaments that support them.
What form of arthritis is an autoimmune disorder in which synovial membranes and other tissues are inflamed and thickens?
Rheumatoid arthrits
Which form of arthritis is an autoimmunedisorder in which synovial membranes and other tissues are inflamed and thicken?
Rheumatoid arthritis is the autoimmune disorder that attacks the synovial membranes of joints and other tissues.
What is a disease characterized by inflamed joints?
You have rheumatoid arthritis, which involve the small joints.
Can cardiac sphincter get inflamed due to severe rheumatoid arthritis flare up and diagnosis simultaneously of pleurisy?
rheumatoid arthritis can cause inflammation in the muscles of the heart and can do the the same in the lining of the lungs leading to pleurisy. The symptoms of rheumatoid arthritis crop up in several places in the body at at the same time.
What diseases and disorders can effect ligaments?
Ligaments can be torn or broken due to injury or fracture, and they can get inflamed in rheumatoid arthritis and infected in septic arthritis
What form of arthritis is a autoimmune disorder in which synovial membranes and other tissues are inflamed and thicken?
Rheumatoid arthritis is an autoimmune disease that leads too connective tissues of the joints as well as many other tissues and organs to become inflamed as a result of attack by the immune system. the exact cause is still unknown and there is no cure for it at present. the disease is also 3 times more prevalent in women then in men.
What is rheumatoid arthritis?
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. RA can be responsible for inflammation around the joints as well as in other organs and tissues of the body. An autoimmune disease is a condition where body's tissues are attacked by the body's own immune system. The immune system is designed to "seek and destroy" invaders or foreign materials of the body, especially infectious organisms. Persons with autoimmune diseases have antibodies in their blood that attack their own body the resulting inflammation then damages or destroys the tissue concerned. Because it can affect several organs of the body it is known as a systemic illness and is sometimes called rheumatoid disease. Rheumatoid arthritis is a chronic illness, meaning it can last for years, patients may experience long periods of time without symptoms. Rheumatoid arthritis is a progressive illness that has the potential to cause joint destruction, Deformity, pain and functional disability. Ra usually presents itself in several joints coinciding on on opposite sides of the body and is also described as a poliarthritis.Kids can get rheumatoid arthritis too. Most people think that it is only the elderly that can get it. The Arthritis Foundation, a nationwide support group, works to bring this message out to the world.Rheumatoid arthritis is an Autoimmune disease that leads to the destruction of connective tissue like cartilage in the joints and in other places.
A disease characterized by inflamed joints?
arthritis
What are the joint symptoms of arthritis?
The term that relates to arthritis in the case of juveniles is "Juvenile idiopathic arthritis" which is an autoimmune disease that usually first shows itself as several joints becoming inflamed and stiff at the same time. For more info on this condition go to the related link below (Juvenile idiopathic arthritis)
Can cardiac sphincter get inflamed due to severe rheumatoid?
Not hat is known of at present.
What is the basic pathology of rheumatoid arthritis?
What are causes and risk factors of rheumatoid arthritis?The cause of rheumatoid arthritis is unknown. Even though infectious agents such as viruses, bacteria, and fungi have long been suspected, none has been proven as the cause. The cause of rheumatoid arthritis is a very active area of worldwide research. It is believed that the tendency to develop rheumatoid arthritis may be genetically inherited (hereditary). Certain genes have been identified that increase the risk for rheumatoid arthritis. It is also suspected that certain infections or factors in the environment might trigger the activation of the immune system in susceptible individuals. This misdirected immune system then attacks the body's own tissues. This leads to inflammation in the joints and sometimes in various organs of the body, such as the lungs or eyes. It is not known what triggers the onset of rheumatoid arthritis. Regardless of the exact trigger, the result is an immune system that is geared up to promote inflammation in the joints and occasionally other tissues of the body. Immune cells, called lymphocytes, are activated and chemical messengers (cytokines, such astumor necrosis factor/TNF, interleukin-1/IL-1, and interleukin-6/IL-6) are expressed in the inflamed areas.Environmental factors also seem to play some role in causing rheumatoid arthritis. For example, scientists have reported thatsmoking tobacco, exposure to silica mineral, and chronic periodontal disease all increase the risk of developing rheumatoid arthritis.What are rheumatoid arthritis symptoms and signs?The symptoms of rheumatoid arthritis come and go, depending on the degree of tissue inflammation. When body tissues are inflamed, the disease is active. When tissue inflammation subsides, the disease is inactive (in remission). Remissions can occur spontaneously or with treatment and can last weeks, months, or years. During remissions, symptoms of the disease disappear, and people generally feel well. When the disease becomes active again (relapse), symptoms return. The return of disease activity and symptoms is called a flare. The course of rheumatoid arthritis varies among affected individuals, and periods of flares and remissions are typical. When the disease is active, symptoms can include fatigue, loss of energy,lack of appetite, low-grade fever, muscle and joint aches, and stiffness. Muscle and joint stiffness are usually most notable in the morning and after periods of inactivity. Arthritis is common during disease flares. Also during flares, joints frequently become red, swollen, painful, and tender. This occurs because the lining tissue of the joint (synovium) becomes inflamed, resulting in the production of excessive joint fluid (synovial fluid). The synovium also thickens with inflammation (synovitis).Rheumatoid arthritis usually inflames multiple joints in a symmetrical pattern (both sides of the body affected). Early symptoms may be subtle. The small joints of both the hands and wrists are often involved. Symptoms in the hands with rheumatoid arthritis include difficulty with simple tasks of daily living, such as turning door knobs and opening jars. The small joints of the feet are also commonly involved, which can lead to painful walking, especially in the morning after arising from bed. Occasionally, only one joint is inflamed. When only one joint is involved, the arthritis can mimic the joint inflammation caused by other forms of arthritis, such as gout or joint infection. Chronic inflammation can cause damage to body tissues, including cartilage and bone. This leads to a loss of cartilage and erosion and weakness of the bones as well as the muscles, resulting in joint deformity, destruction, and loss of function. Rarely, rheumatoid arthritis can even affect the joint that is responsible for the tightening of our vocal cords to change the tone of our voice, the cricoarytenoid joint. When this joint is inflamed, it can cause hoarseness of the voice. Symptoms in children with rheumatoid arthritis include limping, irritability, crying, and poor appetite.
Why do arthritis attack people?
Rheumatoid arthritis is a chronic joint disease that damages the joints of the body. It is also a systemic disease that potentially affects internal organs of the body and leads to disability. The joint damage is caused by inflammation of the joint lining tissue. Inflammation is normally a response by the body's immune system to "assaults" such as infections, wounds, and foreign objects. In rheumatoid arthritis, the inflammation is misdirected to attack the joints. Rheumatoid arthritis is often referred to as RA.The inflammation in the joints causes pain, stiffness, swelling, and loss of function.The inflammation often affects other organs and systems of the body, including the lungs, heart, and kidneys.If the inflammation is not slowed or stopped, it can permanently damage the affected joints and other tissues.Rheumatoid arthritis should not be confused with other forms of arthritis, such as osteoarthritis or arthritis associated with infections. Rheumatoid arthritis is an autoimmune disease. This means that the body's immune system mistakenly attacks the tissues it is supposed to protect.The immune system produces specialized cells and chemicals, which are released into the bloodstream and begin to attack body tissues.This abnormal immune response causes inflammation and thickening of the membrane (synovium) that lines the joint. Inflammation of the synovium is called synovitis and is the hallmark of an inflammatory arthritis such as rheumatoid arthritis.As the synovitis expands inside and outside of the joint, it can damage the bone and cartilage of the joint and the surrounding tissues, such as ligaments, tendons, nerves, and blood vessels.Rheumatoid arthritis most often affects the smaller joints, such as those of the hands and/or feet, wrists, elbows, knees, and/or ankles, but any joint can be affected. The symptoms often lead to significant discomfort and disability.Many people with rheumatoid arthritis have difficulty carrying out normal activities of daily living, such as standing, walking, dressing, washing, using the toilet, preparing food, and carrying out household chores.The symptoms of rheumatoid arthritis interfere with work for many people. As many as half of those with rheumatoid arthritis are no longer able to work 10-20 years after their condition is diagnosed.On average, life expectancy is somewhat shorter for people with rheumatoid arthritis than for the general population. This does not mean that everyone with rheumatoid arthritis has a shortened life span. Rheumatoid arthritis itself is not a fatal disease. However, it can be associated with many complications and treatment-related side effects that can contribute to premature death.Although rheumatoid arthritis most often affects the joints, it is a disease of the entire body. It can affect many organs and body systems besides the joints. Therefore, rheumatoid arthritis is referred to as a systemic disease.Musculoskeletal structures: Damage to muscles surrounding joints may cause atrophy (shrinking) that results in weakening. This is most common in the hands. Atrophy also may result from not using a muscle, usually because of pain or swelling. Damage to bones and tendons can cause deformities, especially of the hands and feet. Osteoporosis and carpal tunnel syndrome are other common complications of rheumatoid arthritis.Skin: Many people with rheumatoid arthritis develop small nodules on or near the joint that are visible under the skin. These rheumatoid nodules are most noticeable under the skin on the bony areas that stick out when a joint is flexed. Dark purplish areas on the skin (purpura) are caused by bleeding into the skin from blood vessels damaged by rheumatoid arthritis. Purpura is particularly common in those patients who have taken cortisone medication. This damage to the blood vessels is called vasculitis, and these vasculitic lesions also may cause skin ulcers.Heart: A collection of fluid around the heart (pericardial effusion) from inflammation is not uncommon in rheumatoid arthritis. This usually causes only mild symptoms, if any, but it can be very severe. Rheumatoid arthritis-related inflammation can affect the heart muscle, the heart valves, or the blood vessels of the heart (coronary arteries). Heart attacks are more frequent in patients with rheumatoid arthritis than those without it.Lungs: Rheumatoid arthritis' effects on the lungs may take several forms. Fluid may collect around one or both lungs and is referred to as a pleural effusion. Inflammation of the lining tissues of the lungs is known as pleuritis. Less frequently, lung tissues may become stiff or scarred, referred to as pulmonary fibrosis. Any of these effects can have a negative effect on breathing. Lung infections become more common.Digestive tract: The digestive tract is usually not affected directly by rheumatoid arthritis. Dry mouth, related to Sjögren's syndrome, is the most common symptom of gastrointestinal involvement. Digestive complications are much more likely to be caused by medications used to treat the condition, such as gastritis (stomach inflammation) or stomach ulcer caused by NSAID therapy. Any part of the digestive tract may become inflamed if the patient develops vasculitis, but this is uncommon. If the liver is involved, it may become enlarged and cause discomfort in the abdomen.Kidneys: The kidneys are not usually affected directly by rheumatoid arthritis. Kidney problems in rheumatoid arthritis are much more likely to be caused by medications used to treat the condition. Nevertheless, severe, long-standing disease can uncommonly lead to a form of protein deposition and damage to the kidney, referred to as amyloidosis.Blood vessels: Inflammation of the blood vessels can cause problems in any organ but is most common in the skin, where it appears as purple patches (purpura) or skin ulcers.Blood: Anemia or "low blood" is a common complication of rheumatoid arthritis. Anemia means that you have an abnormally low number of red blood cells and that these cells are low in hemoglobin, the substance that carries oxygen through the body. (Anemia has many different causes and is by no means unique to rheumatoid arthritis.) A low white blood cell count (leukopenia) can occur from Felty's syndrome, a complication of rheumatoid arthritis that is also characterized by enlargement of the spleen.Nervous system: The deformity and damage to joints in rheumatoid arthritis often lead to entrapment of nerves. Carpal tunnel syndrome is one example of this. Entrapment can damage nerves and may lead to serious consequences.Eyes: The eyes commonly become dry and/or inflamed in rheumatoid arthritis. This is a result of inflammation of the tear glands and is called Sjögren's syndrome. The severity of this condition depends on which parts of the eye are affected. There are many other eye complications of rheumatoid arthritis, including inflammation of the whites of the eyes (scleritis), that often require the attention of an ophthalmologist.Like many autoimmune diseases, rheumatoid arthritis typically waxes and wanes. Most people with rheumatoid arthritis experience periods when their symptoms worsen (known as flares or active disease) separated by periods in which the symptoms improve. With successful treatment, symptoms may even go away completely (remission, or inactive disease).About 1.3 million people in the United States are believed to have rheumatoid arthritis.About 75% of these are women. Women are two to three times more likely to develop rheumatoid arthritis than men.Rheumatoid arthritis affects all ages, races, and social and ethnic groups.It is most likely to strike people 35-50 years of age, but it can occur in children, teenagers, and elderly people. (A similar disease affecting young people is known as juvenile rheumatoid arthritis.)Worldwide, about 1% of people are believed to have rheumatoid arthritis, but the rate varies among different groups of people. For example, rheumatoid arthritis affects about 5%-6% of some Native-American groups, while the rate is very low in some Caribbean peoples of African descent.The rate is about 2%-3% in people who have a close relative with rheumatoid arthritis, such as a parent, brother or sister, or child.Although there is no cure for rheumatoid arthritis, the disease can be controlled in most people. Early, aggressive therapy, soon after the initial diagnosis, is optimally targeted to stop or slow down inflammation in the joints can prevent or reduce symptoms, prevent or reduce joint destruction and deformity, and prevent or lessen disability and other complications.
