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A disease is an abnormal condition affecting the body of an organism. It is often construed to be a medical condition associated with specific symptoms and signs. It may be caused by external factors, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune diseases. There are four main types of disease: pathogenic disease, deficiency disease, hereditary disease, and physiological disease. In many cases, the terms disease, disorder, morbidity and illness are used interchangeably. In some situations, specific terms are considered preferable.

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