Articular cartilage, is responsible for the low friction and painless, articulation of synovial joints. Articular cartilage consists of a sparse distribution of highly specialized cells known as chondrocytes. These are are embedded in a matrix to provide articular cartilage withwonderful mechanical properties. Chondrocytes make up the tissue matrix macromolecular framework from three classes of molecules known as collagens, proteoglycans, and noncollagenous proteins. The Chondrocytes protect the cells from being damaged as a result of normal joint use, they determine the types and concentrations of molecules reaching the cells, acts as a mechanical signal transducer for the cells, and helps maintain the chondrocyte phenotype. Articular cartilage undergoes internal remodeling Throughout life as cells replace matrix macromolecules lost as a result of degradation. Aging decreases the ability of chondrocytes become less able to maintain and restore articular cartilage leading to an increase in the risk of degeneration of the articular cartilage surface. Progressive degeneration of articular cartilage leads to joint pain and dysfunction. This situation is clinically identified as osteoarthritis. Investigation regarding the pathogenesis of post traumatic osteoarthritis, the form of osteoarthritis that develops following joint injury, is helping to explain the development and progression of joint degeneration.
Yes any injury to sites that involve the joints can lead to osteoarthritis.
Osteoarthritis is not caused by a lack of calcium. Osteoarthritis is the result of the wearing down of cartilage in the joints of the body and is most prevalent in the big weight bearing joints.
yes
Yes. Any person can develop osteoarthritis, regardless of any other previous conditions.
Yes you can osteoarthritis can lead to debilitating joint damage that can in turn be crippling.
The medical term for the form of arthritis that is commonly known as wear-and-tear arthritis is osteoarthritis.
osteoarthritis affecting many vertebrae.
"degenerative arthritis" and "osteoarthritis"
Bristol University - Obesity and osteoarthritis
Osteoarthritis is adisorder of the joints characterized by progressive deterioration of articular cartilage.
Yes any injury to sites that involve the joints can lead to osteoarthritis.
It can certainly be involved in the formation of osteoarthritis.
Osteoarthritis can not be cured, however there are quite a few things that can be done to help the sufferer of osteoarthritis. Go to the link below (Osteoarthritis treatments) for information that may be helpfull.
Osteoarthritis is not caused by a lack of calcium. Osteoarthritis is the result of the wearing down of cartilage in the joints of the body and is most prevalent in the big weight bearing joints.
yes
No, it is not infectious.
Any injury to a joint can lead to to osteoarthritis