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Cushing syndrome may be caused by taking too much corticosteroid medications, such as prednisone and prednisolone. These drugs are used to treat conditions such as Asthma and rheumatoid arthritis.

Other people develop Cushing syndrome because their bodies produce too much cortisol, a hormone normally made in the adrenal gland. Causes of too much cortisol are:

Cushing's disease, when the pituitary gland makes too much of the hormone ACTH. ACTH then signals the adrenal glands to produce cortisol. Tumor of the pituitary gland may cause this condition.

Tumor of the adrenal gland

Tumor elsewhere in the body that produces cortisol

Tumors elsewhere in the body that produce ACTH (such as the pancreas, lung, and thyroid)

Symptoms

Most people with Cushing syndrome will have:

Upper body obesity (above the waist) and thin arms and legs

Round, red, full face (moon face)

Slow growth rate in children

Skin changes that are often seen:

Acne or skin infections

Purple marks (1/2 inch or more wide) called striae on the skin of the abdomen, thighs, and breasts

Thin skin with easy bruising

Muscle and bone changes include:

Backache, which occurs with routine activities

Bone pain or tenderness

Collection of fat between the shoulders (buffalo hump)

Thinning of the bones, which leads to rib and spine fractures

Weak muscles

Women with Cushing syndrome often have:

Excess hair growth on the face, neck, chest, abdomen, and thighs

Menstrual cycle becomes irregular or stops

Men may have:

Decreased fertility

Decreased or no desire for sex

Impotence

Other symptoms that may occur with this disease:

Mental changes, such as depression, anxiety, or changes in behavior

Fatigue

Headache

High blood pressure

Increased thirst and urination

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Related Questions

What is the medical term meaning the result of prolonged exposure to high levels of cortisol?

Cushing's Syndrome


Icd-9 code for cushing's syndrome?

E24.9 - Cushing's syndrome, unspecified


How many people die a year from Cushing. Sydrome?

Cushing's syndrome is a rare condition caused by prolonged exposure to high levels of cortisol. It does not typically result in death directly, but complications related to the condition such as heart disease, infections, or organ failure can lead to mortality. The exact number of deaths specifically attributed to Cushing's syndrome per year is unknown.


What is the concept of cushing about?

"Cushing" refers to Cushing's syndrome, an issue that results from high exposures to the hormone cortisol. The syndrome will result in a tumor appearing on the pituitary gland.


What has the author Dorothy T Krieger written?

Dorothy T. Krieger has written: 'Cushing's syndrome' -- subject(s): Cushing's syndrome


Cushing syndrome is associated with an excess of?

cortisol


How is hypernatremia related to cushing's disease?

Cushing syndrome affects the adrenal gland, which in return stimulates aldosterone. Aldosterone is responsible for salt and water retention. In Cushing syndrome cortisol is high which also blocks the excretion of sodium from the body.


Cushing syndrome results from hypersecretion of glucocorticoid hormone by a tumor of the adrenal cortex?

True: Cushing syndrome affects more women than men. The hypersecretion of glucocorticoid hormone causes patients with Cushing syndrome to develop a characteristic moon face. Redistribution of body fat causes a buffalo hump on the upper back.


What is the disease that causes obesity?

Cushing syndrome, Prader Willi syndrome, and Simpson-Golabi-Behmel Syndrome can all cause obesity.


What disease has Moon face and buffalo hump as symptoms?

Cushing's syndrome


What factors cause alkalosis?

Hyperventilation,Cushing's syndrome,severe dehydratation


What is also known as hypercortisolism?

Endogenous hypercortisolism is known as Cushing's syndrome.