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the tobacco buzz is because nicotine is a chemical that acts on nicotinic acetlycholine receptors, which are neurotransmitters. nicotine also releases dopamine, a reward system chemical ... it also acts as an MAOI inhibitor, monoamine oxidase breaks down other neurotransmitters such as dopamine, serotonin and norepinephrine. so it acts on alot of chemicals, some directly and some indirectly by inhibiting the breakdown of the neurotransmitters.

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