Why is it necessary to pre-clot a vascular graft that is made of knitted polyester?

Answer 1

Pre-clotting a knitted polyester vascular graft is necessary to enhance its biocompatibility and promote early vascularization. The pre-clotting process involves the formation of a fibrin layer on the graft surface, which helps to create a more favorable environment for cellular ingrowth and integration with surrounding tissues. This can significantly reduce the risk of thrombosis and improve long-term patency of the graft. Additionally, it may aid in minimizing inflammation and promoting healing post-surgery.