If you keep it maintained well and don't push the engine to hard it will likely last 300-350k miles. I have a 01 3.3 with 130k and it still runs like new but I work with cars and trucks and I have seen many just like it on the original engine with 250k-270k but I have also seen them having engine failure with like 100k miles from poor maintenance. Just keep the fluids fresh and the timing belt changed when suggested.
It's hard to say if they are going to be as durable as the old hardbody, we used to have a 86 that took a beating for 10 years and we sold it in 1994 with over 300k miles and we still see it driving around from time to time.
The 2005 Nissan Frontier has an inline 4 engine.
The 2006 Nissan Frontier has an inline 4 engine.
The 2010 Nissan Frontier has an inline 4 engine.
The 2004 Nissan Frontier has an inline 4 engine.
The 2008 Nissan Frontier has an inline 4 engine.
The 2002 Nissan Frontier has an inline 4 engine.
The 2007 Nissan Frontier has an inline 4 engine.
The 2009 Nissan Frontier has an inline 4 engine.
The 2001 Nissan Frontier has an inline 4 engine.
The 2011 Nissan Frontier has an inline 4 engine.
The 2003 Nissan Frontier has an inline 4 engine.
The 2014 Nissan Frontier has an inline 4 engine.