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The oil filter in a 2010 RX350 is not your typical oil filter, meaning it's not a canister type where you can simply unscrew one filter and screw on a new one.

The filter is located just forward of the drain plug. Removal of the plastic covers under the engine compartment will provide access to the filter and pan drain plug.

The filter is an element replacement only (along with two O rings for sealing). The replacement filter element also comes with a drain tube to help drain residual oil in the filter canister. Drain the oil first, and then remove the element. Replace the O rings and reassemble.

For help locating the filter, use the diagrams posted here. While this is not the filter type replacement for the 2010 (this is a 2008, but has great pictures for the location), it is helpful.

http://us.lexusownersclub.com/forums/index.php?showtopic=21979

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