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The Apollo 1 spacecraft did catch fire and burn up, killing the crew of three, during a training exercise on the launchpad in 1967. That however was just a trainig exercise, not an actual attempt to launch, and had that mission evenutally gone forward it was just going to be a test of the spacecraft in Earth orbit, not a lunar mission. Although Apollo 13 did have to be aborted it returned to Earth succesfully and without casualties. The other missions were all successful.

A few more died in training. For example, Charlie Bassett and Elliot M See, the original crew for Gemini 9. Since Gemini was developmental work for the moonshot program, all these guys can be counted as well. Challenger and Columbia DeathsThe loss of the shuttles Challenger and Columbia claimed the lives of seven astronauts each time. There have also been at least four Soviet deaths in the Soyuz programs and many more on the ground. You can find information on all deaths at the web links on the left.

Russian space program deathsVladimir Komarov died on board of Soyuz 1 when parachute failed to open during reentry.

Georgi Dobrovolski, Viktor Patsayev and Vladislav Volkov died on board of Soyuz 11 when vehicle decompressed on approach to reentry.

Total of 22 people were killed in space relaed accidents,according to Wikipedia.

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