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The main issue with staying in space too long is the detrimental effects of prolonged exposure to microgravity on the human body. This includes muscle atrophy, bone density loss, and changes in fluid distribution, which can lead to cardiovascular problems. Additionally, extended space missions expose astronauts to higher levels of cosmic radiation, increasing the risk of cancer and other health issues. Psychological challenges, such as isolation and confinement, can also impact mental well-being during long-duration missions.

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