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Marfan is an autosomal dominant disorder, which means that if someone inherits a defected gene from either parent, he will have Marfan syndrome. 75% of people with Marfan got it from their parents; the other 25% were the result of random mutations that happened in the first days or weeks of the pregnancy.
This syndrome is caused by a mutation in the FBN1 gene on chromosome 15, which is necessary for structural and maintenance of elastic, connective tissue fibers. Everyone has this gene in them. There are over 600 different mutations on FBN1 that can cause Marfan. FBN1 mutations can also result in other disorders as well, like ectopia lentis and MASS Phenotype.
What else can I help you with?
What are the chances of getting marfan syndrome?
Marfan syndrome is found in 1 in every 5,000 - 10,000 births. If one of your parents has Marfan syndrome, you have a 50% chance of having Marfan syndrome.
Is marfan syndrome automsomal dominant?
Yes, Marfan syndrome is autosomal dominant.
What does Marfan syndrome mean?
Marfan Syndrome is a medical problem with the Conective Tissue.
Is Marfan syndrome contagious?
Marfan's syndrome is not contagious. A person can only get it by inheriting it from a parent.
Is Down Syndrome the same as Marfan Syndrome?
No. Down is caused by an extra chromosome while Marfan is due to a mutation in one or more genes.
What effects can marfan syndrome have on a persons life?
They cant exercise as vigorously as someone without Marfan syndrome
What can be some symptoms for Marfan's syndrome?
flat feet an sinked chest are some symptomes of marfan syndrome
Can animals have marfan syndrome?
Marfan syndrome is not naturally found in animals. However, researchers have created mice with Marfan syndrome in laboratories for the purpose of testing medications on them before conducting human trials.
What is the etiology of marfan syndrome?
The etiology of marfan syndrome would be the mutations in the protein FBN1 in the gene chromosome 15.
How many people in the world haves marfan syndrome?
1 in every 5,00o to 7,000 people have Marfan syndrome.
What is the most serious complication from Marfan syndrome?
Aortic enlargement. This is the most serious potential complication of Marfan syndrome.
What important genetic characteristic does Marfan syndrome have?
Another important genetic characteristic of Marfan syndrome is variable expression.
