There is no mention of Anne in The Bible. What we know about her is through tradition and non-canonical writings. She was the mother of the Blessed Virgin Mary and grandmother of Jesus. There is no record of any nicknames but she would have been called by her family (in Aramaic, of course) Mom, Mother, Grandma, Grandmother or Nana.
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Anne, the mother of the Blessed Virgin Mary, was a mother and housewife. As far as we know, she was not employed outside of the home.