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R-422B is an HFC, therefore no license required.

HFC - R422B

R-422B (NU-22B) is a retrofit blend from ICOR that is designed to match R-22 in air conditioning and refrigeration applications. No system components need to be changed, nor does the oil need to be flushed, when retrofitting to R-422B. Systems that were previously retrofitted to R-417A (NU-22) can be serviced (topped off) or recharged with R-422B, providing a boost in capacity and run-time properties that more closely match R-22. The hydrocarbon component in R-422A helps promote oil return in systems containing mineral oil or alkylbenzene. Although HFC refrigerants won't mix with these oils, the hydrocarbon addition thins the oil and keeps it moving around the loop. More complicated piping arrangements or large hold-up volumes may still require some oil be changed to POE.

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