The shortest distance is 470 miles.
Buffalo, NY to Hilton Head Island, SC is about 900 road miles.
920 miles
The shortest driving distance is 247 miles.
Take I-95 SOUTH to US-278 to JASPER and HILTON HEAD ISLAND at EXIT 8 in SOUTH CAROLINA. On this route, bypass Richmond via I-295 (EXIT 84A.)Turn left off the exit ramp onto US-278 EAST to HILTON HEAD ISLAND. Take US-278 EAST to Hilton Head Island.
It is 115.77 miles according to MapQuest.
800 miles
The shortest driving distance is 247 miles.
It is 288.03 miles according to MapQuest.
It is 312 miles according to Google Maps.
It is 150 miles according to Google Maps.
It is 134 miles according to Google Maps.
Hilton Head Island, SC, is approximately 30 miles off Interstate 95. The closest exit to access Hilton Head from I-95 is Exit 8, which leads to US Highway 278. The drive from the interstate to the island typically takes around 30 to 40 minutes, depending on traffic.