You did not specify which Spartanburg was being referred to, so:
Spartanburg, IN to Charlotte, NC is approximately: 511.82miles
Spartanburg, SC to Charlotte, NC is approximately: 74.24miles.
There are 57 miles between Spartanburg, SC, and Asheville, NC (as the bird flies).
124 miles taking this route:Take U.S. 64 EAST to I-26 EAST to SPARTANBURG. This is in the town of Hendersonville.Take I-26 EAST to U.S. 74 EAST to COLUMBUS and RUTHERFORDTON at EXIT 67.Stay on U.S. 74 EAST to I-85 towards CHARLOTTE and SPARTANBURG. You want I-85 NORTH to CHARLOTTE.Take I-85 NORTH to CHARLOTTE.
It takes around an hour and a half.
Charlotte NC is the closest point of entry into the state from Spartanburg SC. The total distance in miles from Spartanburg SC to Charlotte NC is 78.48 miles. The total travel distance in time is 1 hour 23 minutes.
100 miles
About 3 hours
110 miles taking this route:Follow U.S. 74 EAST via I-26 EAST (exit at EXIT 67 off I-26 to continue EAST on U.S. 74) to I-85 & U.S. 29 SOUTH to CHARLOTTE and SPARTANBURG. You want to take I-85 NORTH towards CHARLOTTE and GASTONIA.Take I-85 NORTH to Charlotte.
The distance is 74.3 miles; about an 80 minute drive up I-85 NORTH.
It is 305 miles according to Google Maps.
Mt. Holly is right outside of Charlotte.
about 200 miles
around 250 miles