It is 231.70 miles according to MapQuest.
231 mi - about 4 hours 17 mins
tuscaloosa is 80 miles north of prattville, al.
225 miles taking this route:Follow U.S. 43 NORTH from Tuscaloosa to U.S. 78 near Hamilton. At JCT U.S. 78, follow signs to U.S. 78 WEST.Take U.S. 78 (FUTURE I-22 CORRIDOR) WEST to Memphis. U.S. 78 is LAMAR AVENUE in Memphis.
209 miles
184 miles
195 miles
607 miles
194 miles both - ways.
155 miles
457 miles
The halfway point between Topeka, Kansas, and Tuscaloosa, Alabama, is approximately near the city of Memphis, Tennessee. This location is along the I-40 corridor, making it a practical stop for travelers. Memphis offers various amenities and attractions, making it an ideal midpoint for a road trip between the two cities.
It is 59.43 miles according to MapQuest.