150 miles taking this route:
Yes, Virgin West Coast to Wolverhampton then Arriva Cross Country to Southampton.
southampton, northampton, wolverhampton
Northampton, Southampton, Brighton, Wolverhampton, Taunton, etc.
Nottingham is 60 miles away from Wolverhampton.
About 12 miles
Its roughly 170 miles from Southampton to Stowmarket via the M3.
120 miles
Southampton, Hampshire to Newark-on-Trent, Nottinghamshire = 177.9 miles.
270 miles
about 30 miles
Assuming you mean the Wolverhampton North Premier Inn hotel on Stafford Road, it is 3.4 miles (10 mins by car) to Molineux Stadium.
68 Miles approximately