That depends on traffic, what roads you use, how many boroughs you're crossing, and what direction you're talking about (north-south or east-west).
How long does it take to drive from Radcliff kentucky to NewYork city
The drive from New York City to Mystic seaport takes at least 3 hours.
15 hours
354 miles
2.5 hours
the 1000
20 hours
Your whole life
About 293.76 miles according to MapQuest.
It takes about 4-5 hours
4 hrs and 30 mins
About 27 hours-