How many driving miles from charlotte North Carolina to gainesville Florida?

Answer 1

500 miles taking this route:

1. Take I-77 SOUTH from Charlotte to I-26 EAST to CHARLESTON (TO I-95) at END I-77 in Columbia, South Carolina.
2. Take I-26 EAST to I-95 SOUTH to SAVANNAH at EXIT 169A.
3. Take I-95 SOUTH to I-10 WEST via I-295 SOUTH to bypass JACKSONVILLE (EXIT 362B off I-95 in Florida to get onto I-295 SOUTH ; EXIT 21B off I-295 to get onto I-10 WEST to LAKE CITY).
4. Take I-10 WEST to I-75 SOUTH to TAMPA at EXIT 296A near Lake City.
5. Take I-75 SOUTH to Gainesville.