MapQuest estimates the driving time as 18 hours and 20 minutes.
about 4 and 1/2 hours
4 hours
About 6 and a half hours.
About four hours.
Santa Cruz is approximately 269.5 miles from Santa Barbara
About 2-3 hours
4 hours
Not far 4-5 hours.
It will require about 5.5 hours to drive that 335 miles via US 101.
According to Google Maps, your drive is about 127 miles - about 2 hours 23 minutes, or up to 4 hours in heavy traffic.
It will take about 6 hours 40 minutes to drive the 400 miles.
About 3 hours, maybe a bit more, but it is a nice drive.