How many miles are there from Panama City FL to Saint Augustine FL?

Answer 1

320 miles taking this route:

1. Take U.S. 231 NORTH form Panama City to I-10 near Cottondale. At JCT I-10, follow signs to I-10 EAST to TALLAHASSEE.
2. Take I-10 EAST to I-95 SOUTH to ST. AUGUSTINE via I-295 SOUTH to bypass JACKSONVILLE (EXIT 356 off I-10 to get onto I-295, follow signs on the exit ramp to I-295 SOUTH to ST. AUGUSTINE ; EXIT 61A off I-295 to get onto I-95 SOUTH to ST. AUGUSTINE).
3. Take I-95 SOUTH to St. Augustine.