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120 miles taking this route:

  1. Take I-26 EAST from Columbia to I-526 EAST to MT. PLEASANT at EXIT 212C near North Charleston.
  2. Take I-526 to U.S. 17 NORTH to GEORGETOWN at EXIT 29 in Mt. Pleasant.
  3. Take U.S. 17 NORTH to SC-517 SOUTH to ISLE OF PALMS. Turn right.
  4. Take SC-517 SOUTH to Isle of Palms.
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