How many miles from Midland Texas to Lafayette Louisiana?

Answer 1

720 miles taking this route:

1. Take I-20 EAST from Midland to I-49 SOUTH to ALEXANDRIA via LA-3132 - BYPASS to bypass Shreveport (EXIT 11 off I-20 in Louisiana, follow signs to LA-3132 EAST; EXIT 7 off LA-3132 to get onto I-49 SOUTH to ALEXANDRIA).
2. Take I-49 SOUTH to Lafayette.