How many miles is it from Louisville KY to Asheville NC?

Answer 1

360 miles taking this route:

1. Take I-64 EAST, from Louisville, to I-75 SOUTH to KNOXVILLE, outside of Lexington.
2. Continue on I-75 SOUTH to I-40 EAST to ASHEVILLE, via I-640 EAST to bypass KNOXVILLE, Tennessee.
3. Take I-40 EAST to ASHEVILLE.