How many miles is it from Nashville TN to Destin FL?

Answer 1

455 miles taking this route:

1. Take I-65 SOUTH from Nashville to U.S. 331 via SOUTH BLVD in Montgomery (EXIT 168 off I-65 in Alabama, turn left off the exit ramp ; right onto U.S. 331 SOUTH).
2. Take U.S. 331 SOUTH to U.S. 98 at END U.S. 331 in Florida (where you literally cannot go ANY further). Turn right onto U.S. 98 WEST to DESTIN.
3. Take U.S. 98 WEST to Destin.