According the AA Route Planner (GB Edition) the distance is 142.2 miles, this will take about 2 hours and 44 minutes to drive, assuming you take the direct route and there are no stops, accidents, breakdowns or other hold ups en route.
283 miles
117 miles by road
The driving distance from Fishguard, Pembrokeshire, UK to Holywell, Flintshire, UK is 143.03mi / 230.19km
145 miles taking this route:Take M4 to The WEST, from London, to A449 MONMOUTH at J24 in SOUTH WALES.Take A449 to A40 MONMOUTH.Continue straight on A40 to Monmouth.
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Fishguard is in Wales, not Ireland. You'll need to take a ferry to get from Fishguard to Dublin or Vice Versa. There are daily ferries, they take a few hours.
The driving distance from Monmouth, Oregon to Medford, Oregon is 230 miles / 371 km
The driving distance is about 250 road miles (403 km).
Distance between London, England, United Kingdom and Dublin, Ireland 291 miles (469 km) (253 nautical miles)
222 miles
251 mi - about 4 hours 38 mins.
Fishguard's population is 5,043.