What is the distance from Columbia SC to Hilton Head SC?

Answer 1

160 miles. This is the best route:

1. Take I-26 EAST to I-95 SOUTH to SAVANNAH at EXIT 169A.
2. Take I-95 SOUTH to U.S. 278 to HARDEEVILLE and HILTON HEAD IS. at EXIT 8.
3. Turn left off the exit ramp onto U.S. 278 EAST. Take U.S. 278 EAST to Hilton Head Island.