What is the distance from Coumbia SC to Florence AL?

Answer 1

497 miles taking this route:

1. Take I-20 WEST to I-65 NORTH to HUNTSVILLE at EXIT 124B off I-20/59 in downtown Birmingham, Alabama.
2. Take I-65 NORTH to U.S. 72 to ATHENS and HUNTSVILLE at EXIT 351.
3. Turn left off the exit ramp onto U.S. 72 WEST. Take U.S. 72 WEST to Florence.