What is the fastest route to Detroit MI from Kingsport TN?

Answer 1

617 miles taking this route:

1. Take I-26 EAST from Kingsport to I-81 SOUTH to KNOXVILLE at EXIT 8A.
2. Take I-81 SOUTH to I-40 WEST to KNOXVILLE at EXIT 1B.
3. Take I-40 WEST to I-75 NORTH to LEXINGTON via I-640 WEST to bypass KNOXVILLE. (EXIT 393 off I-40 to get onto I-640 WEST ; EXIT 3A off I-640 to get onto I-75, follow signs to I-75 NORTH to LEXINGTON.)
4. Take I-75 NORTH to Detroit.