What is the shortest route from Tallahassee FL to Brunswick GA?

Answer 1

The shortest route goes through Valdosta and Waycross.

East 90 to 146 to North 221 to East 84 to East 82

Taking I-10 East to Jacksonville, North on the 295 Beltway to I-95 North is longer, but faster.

What you do for this best route is:

1. Take I-10 EAST, from Tallahassee, to I-95 NORTH to SAVANNAH, via I-295 BELTWAY - NORTH to bypass JACKSONVILLE (EXIT 356 off I-10 to get onto I-295 NORTH to SAVANNAH ; EXIT 35B off I-295 to get onto I-95 NORTH to SAVANNAH).
2. Take I-95 NORTH to Brunswick.