Both places are very nice, but for my money Marco Island has much less Traffic and much easier to get around in.
it is about 50 miles from fort Myers airport to Marco island
The nearest airport is the Naples Municipal Airport, about 15 miles from Marco Island.
55 miles taking this route:Take CR-951 (COLLIER BLVD) - NORTH, from Marco Island, to I-75 NORTH to TAMPA.Take I-75 NORTH to FT. MYERS.
Fort Myers to Marco Island is 57.24 miles and would take 1 hour and 6 minutes to drive. [Source: Mapquest]
50 miles
50 miles taking this route:Take I-75 SOUTH, from Ft. Myers-Southwest Florida Int'l Airport, to CR-951 to MARCO ISLAND at EXIT 101.Take CR-951 SOUTH (Collier Blvd) to Marco Island.
51 miles
It is 47 miles according to Google Maps.
On the southwest coast of Florida, south of Fort Myers, just above the Everglades.
It is 47.3 miles according to Google Maps.
50 miles taking this route:Take I-75 SOUTH to FL-951/84 to NAPLES and MARCO ISLAND at EXIT 101.Turn right off the exit ramp onto FL-951 SOUTH. Take FL-951 SOUTH to Marco Island.
The nearest major airport is Naples Municipal Airport(APF / KAPF). This airport has domestic flights from Naples, Florida and is about 19 driving miles from the center of Marco Island.Another major airport is Southwest Florida International Airport (RSW / KRSW), which has international and domestic flights from Fort Myers, Florida and is 50 road miles from Marco Island.