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The poultice onion, Allium cepa, has been used to treat acne as it has mild exfoliating, anti-fungal and anti-bacterial properties due to the presence of thiols, or sulfur containing compounds. It contains flavonoids as well, which also impart anti-oxidant and anti-inflammatory properties. However, it can be irritating to the skin, and the malodor has limited its use in lotions. However, scar medications such as Mederma and anti-dandruff lotions such as Vaipani do contain onion extract.

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