Can you please Tell about the gel clot method of BET?

Answer 1

The gel clot method of the bacterial endotoxin test, or BET, is a 60-minute test. This is wherein sample are tested to determine the endotoxin content.

Answer 2

The gel clot method is a qualitative test used for bacterial endotoxin detection in pharmaceuticals. This method involves adding a sample to a tube containing a gel clot reagent that will gel in the presence of endotoxins. If endotoxins are present in the sample, a gel will form, indicating a positive result for endotoxin contamination. The gel clot method is simple and cost-effective but has limitations in terms of sensitivity compared to other methods like the chromogenic or turbidimetric methods.