Describe how the karyotype of an XXY human would differ from that of an XO human?

Answer 1

The karyotype of an XO human would be deficient one X chromosome, compared to that of a normal female, and it would result in a female. Normal human females only use one X chromosome, whereby one is inactivated, which is why an XO human is viable. An XXY human would have one extra X chromosome as compared to that of a normal male, and it would result in a male. Again, an X chromosome is inactivated, which is why an XXY human is viable. XO is referred to as Turner Syndrome. XXY is referred to as Klinefelter Syndrome.

Answer 2

An XXY individual would have an additional sex chromosome (a total of 47 chromosomes), resulting in Klinefelter syndrome. In contrast, an XO individual would have only one sex chromosome (a total of 45 chromosomes), typically resulting in Turner syndrome.