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There are not 2 main organs in a human body. I can think of about 7 organs without witch you would not survive for long. But since you put question that way, I guess the most natural response would be brain and heart (although without lungs your brain would not have must use). The function of the heart is to circulate the blood around your body, to supply oxygen and many more chemicals to all your organs and tissues. The function of the brain is to coordinate your nervous system.

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