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Archaea do not have an endoplasmic reticulum. The prokaryotic cell has a nucleoid region with no actual membrane- bound nucleus. Ribosomes on the rough endoplasmic reticulum in eukaryotic cells translate mRNA into proteins. This process is preceded by transcription occurring in the nucleus. So, archaea having no nucleus do not require an endoplasmic reticulum to translate DNA, they simply use ribosomes in proximity to the nucleoid region.

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