By using multiple origins of the replication on each chromosome, which results in multiple replicons.
Telomerase ends become shorter as humans age. This happens in part because of the process known as the end replication problem, whereby strands of DNA become uneven over time.
bacteria cannot remove eukaryotic introns; bacterial dna does not contain introns like eukaryotic genes do so they had to be removed before being added to the plasmid.
The problem of replication could not be worked out in triple helix.
Evolutionists say that the smaller the animal the smaller the number of chromosomes.
The two strands of a DNA molecule are antiparallel to one another (the backbone of one strand runs from 5'-3' while the complimentary strand runs 3'-5'). Unfortunately, DNA polymerase, the enzyme responsible for replicating DNA, can only make DNA in a 5'-3' direction (and read DNA in the 3'-5' direction). Also, it needs a "primer" to give it a place to bind and start replication. So this creates a problem when synthesizing the 3'-5' stand because your enzyme will only synthesize 5'-3'. During replication this is solved by synthesizing small pieces of DNA ahead of the replication fork on the 5'-3' mother strand. Thus we have one daughter strand which is synthesized as a continuous piece of DNA (called the leading strand) and one daughter strand which is synthesized in small, discontinuous pieces (called the lagging strand). However, at the extreme end of the DNA, we run into another problem. The leading stand can be made to the very end, but the lagging strand cannot because you need the RNA primer upstream to begin each piece of the lagging strand DNA but at the end of the DNA there is nothing for this piece to attach to. Thus, the last section of the lagging strand cannot be synthesized and after several rounds of DNA replication, the DNA molecule gets smaller and smaller. This is "the end of replication problem" and it is solved by putting a DNA cap on the ends of DNA called a telomere which does not code for any protein, thus when this information is lost it does not have severe consequences for the cell.
The replication begins at origins along the DNA.
Telomeres solve the end replication problem by extending the 3' end of the chromosome. Without them, the 3' end can't be replicated since replication is 5' to 3'.
There is no limit.
It is a programming problem in which the objective function is to be optimised subject to a set of constraints. At least one of the constraints or the objective functions must be non-linear in at least one of the variables.
financial constraints and lack of expansion
a mainframe computer is required
Four constraints should be taken in optimal placement of capacitor problem for voltage improvement using the Particle Swarm Optimization.
Telomerase ends become shorter as humans age. This happens in part because of the process known as the end replication problem, whereby strands of DNA become uneven over time.
compartmentalizing cellular functions into various organelles
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One. To be a (non-trivial) linear programming problem both the objective function and the constraints must be linear. If there were no constraints then the objective function could be made arbitrarily large or arbitrarily small. (Think of a line in two-space.) By adding one constraint the objective function's value can be limited to a finite value.
It depends on factors such as available resources, time constraints, and feasibility of data collection methods. Conducting a pilot study or literature review can help determine the feasibility of the research problem.